Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p049 | (1) | WCRB2014

Nucleoli are formed in developing mouse embryos without nucleolus precursor bodies

Kyogoku Hirohisa , Fulka Josef , Kitajima Tomoya S , Wakayama Teruhiko , Miyano Takashi

Introduction: The large, compact oocyte nucleoli, sometimes referred to as nucleolus precursor bodies (NPBs), are essential for embryonic development in mammals. It has been convincingly documented that zygotes inherit the oocyte nucleolar material and form NPBs again in pronuclei. During early embryonic development, the compact zygote NPBs gradually transform into reticulated nucleoli of somatic cells type. Here we show that zygote NPBs are not required for embryonic and full...